#Dendrite neuron update#

There are many synaptic boutons on these dendrites. Dendrites of magnocellular paraventricular nucleus oxytocin neurons project toward the third ventricle. The dendrites of supraoptic nucleus oxytocin neurons are broad and bundled together in the ventral glial lamina of the nucleus. Brunton, in Encyclopedia of Neuroscience, 2009 Dendrites A better understanding of how defects in RGC dendrites contribute to neurodegeneration in glaucoma might provide new insights into disease onset and progression, while informing the development of novel therapies to prevent vision loss.

#Dendrite neuron update#

Here, we provide an update on recent work addressing the role of RGC dendritic degeneration in models of acute and chronic optic nerve damage as well as novel mechanisms that regulate RGC dendrite stability.

Recent data indicate that axonal injury triggers rapid structural alterations in RGC dendritic arbors, prior to manifest axonal loss, which lead to synaptic rearrangements and functional deficits. In glaucoma, damage to RGC axons results in progressive neurodegeneration and vision loss. Retinal ganglion cell (RGC) dendrites receive synaptic inputs from bipolar and amacrine cells, thus allowing cell-to-cell communication and flow of visual information. Jessica Agostinone, Adriana Di Polo, in Progress in Brain Research, 2015 AbstractДendrites are exquisitely specialized cellular compartments that critically influence how neurons collect and process information. This new data adds to our understanding of the incredible complexity of neuronal transmission.

Although dendrites have traditionally been regarded as receivers of the neurotransmission, recent research has found that dendrites can also release neurotransmitters into the synapse (Stuart et al., 2008). Dendrites integrate this stimulation (from a multitude of receptors) and play a crucial role in determining the extent to which the received stimulation will result in an action potential. The surface of the dendrites is filled with receptors that become enacted upon by neurotransmitters that traversed the synapse after the pre-synaptic neuron fired and released neurotransmitters into the synapse. They resemble a tree-like structure, forming projections that become stimulated by other neurons and conduct the electrochemical charge to the cell body (or, more rarely, directly to the axons). Kapalka, in Nutritional and Herbal Therapies for Children and Adolescents, 2010 The DendritesДendrites are appendages that are designed to receive communications from other cells.